{"id":9625,"date":"2022-02-18T10:45:49","date_gmt":"2022-02-18T03:45:49","guid":{"rendered":"http:\/\/cstc.vn\/blogtsk\/?p=9625"},"modified":"2022-02-18T10:45:49","modified_gmt":"2022-02-18T03:45:49","slug":"thuoc-dieu-tri-viem-khop-co-the-cuu-song-benh-nhan-covid-can-may-tho","status":"publish","type":"post","link":"https:\/\/cstc.vn\/blogtsk\/thuoc-dieu-tri-viem-khop-co-the-cuu-song-benh-nhan-covid-can-may-tho\/","title":{"rendered":"Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp c\u00f3 th\u1ec3 c\u1ee9u s\u1ed1ng b\u1ec7nh nh\u00e2n COVID c\u1ea7n m\u00e1y th\u1edf"},"content":{"rendered":"<p><span>Theo m\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi, nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh n\u1eb7ng v\u1edbi COVID-19 c\u1ea7n h\u1ed7 tr\u1ee3 h\u00f4 h\u1ea5p \u0111\u00e3 s\u1ed1ng s\u00f3t v\u1edbi t\u1ef7 l\u1ec7 cao h\u01a1n c\u00f3 \u00fd ngh\u0129a th\u1ed1ng k\u00ea khi \u0111\u01b0\u1ee3c ng\u1eabu nhi\u00ean d\u00f9ng thu\u1ed1c ch\u1ed1ng vi\u00eam baricitinib. <\/span><\/p>\n<p><span>Baricitinib l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c thay th\u1ebf, ban \u0111\u1ea7u \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n cho b\u1ec7nh vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p. N\u0103m ngo\u00e1i, C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m \u0111\u00e3 ban h\u00e0nh Gi\u1ea5y ph\u00e9p S\u1eed d\u1ee5ng Kh\u1ea9n c\u1ea5p s\u1eeda \u0111\u1ed5i \u0111\u1ec3 baricitinib \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng m\u1ed9t m\u00ecnh trong COVID-19. L\u00fac \u0111\u1ea7u, n\u00f3 \u0111\u01b0\u1ee3c ph\u00ea duy\u1ec7t k\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c kh\u00e1ng vi-r\u00fat <\/span><span>remdesivir<\/span><span>. <\/span><\/p>\n<p><span>T\u00e1c gi\u1ea3 Vincent Marconi, gi\u00e1o s\u01b0 y khoa v\u00e0 s\u1ee9c kh\u1ecfe to\u00e0n c\u1ea7u t\u1ea1i Tr\u01b0\u1eddng Y \u0110\u1ea1i h\u1ecdc Emory v\u00e0 Tr\u01b0\u1eddng Y t\u1ebf C\u00f4ng c\u1ed9ng Rollins, cho bi\u1ebft: \u201cC\u00f3 r\u1ea5t \u00edt l\u1ef1a ch\u1ecdn cho nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh n\u1eb7ng v\u1edbi COVID-19 n\u00ean nh\u1eefng ph\u00e1t hi\u1ec7n n\u00e0y r\u1ea5t \u0111\u00e1ng kh\u00edch l\u1ec7. Ch\u00fang t\u00f4i \u0111\u00e3 c\u00f3 th\u1ec3 ch\u1ee9ng minh r\u1eb1ng lo\u1ea1i thu\u1ed1c thay th\u1ebf n\u00e0y c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 t\u1ef7 l\u1ec7 t\u1eed vong trong 60 ng\u00e0y \u1edf nh\u00f3m c\u00f3 nguy c\u01a1 cao n\u00e0y.\u201d <\/span><\/p>\n<p><span>Marconi v\u00e0 c\u00e1c \u0111\u1ed3ng nghi\u1ec7p \u0111\u00e3 th\u1ef1c hi\u1ec7n nghi\u00ean c\u1ee9u t\u1ea1i 18 b\u1ec7nh vi\u1ec7n \u1edf Hoa K\u1ef3, bao g\u1ed3m B\u1ec7nh vi\u1ec7n Grady Memorial v\u00e0 Atlanta VAMC, c\u00f9ng v\u1edbi c\u00e1c b\u1ec7nh vi\u1ec7n \u1edf Argentina, Brazil v\u00e0 Mexico, t\u1eeb th\u00e1ng 12 n\u0103m 2020 \u0111\u1ebfn th\u00e1ng 4 n\u0103m 2021. <\/span><\/p>\n<p><span>L\u00e0 m\u1ed9t n\u1ed7 l\u1ef1c kh\u00e1m ph\u00e1 \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh c\u00f9ng v\u1edbi nghi\u00ean c\u1ee9u COV-BARRIER do Eli Lilly t\u00e0i tr\u1ee3 (h\u01a1n 1.500 b\u1ec7nh nh\u00e2n), \u0111\u00e2y l\u00e0 m\u1ed9t nghi\u00ean c\u1ee9u ng\u1eabu nhi\u00ean v\u1ec1 baricitinib tr\u00ean 101 <\/span><span>b\u1ec7nh nh\u00e2n ICU th\u1edf m\u00e1y<\/span><span>, m\u1ed9t n\u1eeda trong s\u1ed1 h\u1ecd nh\u1eadn \u0111\u01b0\u1ee3c thu\u1ed1c nghi\u00ean c\u1ee9u trong khi ng\u01b0\u1eddi kia nh\u1eadn \u0111\u01b0\u1ee3c gi\u1ea3 d\u01b0\u1ee3c. <\/span><span>Sau 60 ng\u00e0y, 62% b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng gi\u1ea3 d\u01b0\u1ee3c \u0111\u00e3 ch\u1ebft so v\u1edbi ch\u1ec9 45% nh\u1eefng ng\u01b0\u1eddi d\u00f9ng baricitinib.<\/span><\/p>\n<p><span>Baricitinib \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m trong m\u1ed9t s\u1ed1 th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng tr\u01b0\u1edbc \u0111\u00e2y, nh\u01b0ng \u0111\u00e2y l\u00e0 th\u1eed nghi\u1ec7m \u0111\u1ea7u ti\u00ean t\u1eadp trung v\u00e0o nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh n\u1eb7ng. Nh\u1eefng ng\u01b0\u1eddi tham gia \u1edf c\u1ea3 hai c\u00e1nh tay nh\u1eadn \u0111\u01b0\u1ee3c ti\u00eau chu\u1ea9n ch\u0103m s\u00f3c, bao g\u1ed3m trong h\u1ea7u h\u1ebft c\u00e1c tr\u01b0\u1eddng h\u1ee3p (86%) m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00e1c: <\/span><span>corticosteroid<\/span><span>. <\/span><\/p>\n<p><span>T\u00e1c gi\u1ea3 E. Wes Ely, gi\u00e1o s\u01b0 y khoa t\u1ea1i Trung t\u00e2m Y t\u1ebf \u0110\u1ea1i h\u1ecdc Vanderbilt, cho bi\u1ebft: \u201cNghi\u00ean c\u1ee9u n\u00e0y cho th\u1ea5y r\u1eb1ng trong s\u1ed1 nh\u1eefng b\u1ec7nh nh\u00e2n COVID \u0111\u00e3 b\u1ecb b\u1ec7nh n\u1eb7ng khi s\u1eed d\u1ee5ng m\u00e1y th\u1edf c\u01a1 h\u1ecdc, th\u00eam baricitinib v\u00e0o ch\u1ebf \u0111\u1ed9 ch\u0103m s\u00f3c th\u00f4ng th\u01b0\u1eddng (steroid). Ti\u1ebfp theo, ch\u00fang t\u00f4i c\u1ea7n th\u00eam c\u00e1c th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf r\u00f5 r\u00e0ng \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh c\u00e1ch c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng s\u1ed1ng s\u00f3t cho nh\u00f3m b\u1ec7nh nh\u00e2n COVID \u1ed1m y\u1ebfu nh\u1ea5t th\u1ebf gi\u1edbi n\u00e0y.\u201d <\/span><\/p>\n<p><span>T\u1ed5 ch\u1ee9c Y t\u1ebf Th\u1ebf gi\u1edbi (WHO) g\u1ea7n \u0111\u00e2y \u0111\u00e3 c\u1eadp nh\u1eadt h\u01b0\u1edbng d\u1eabn c\u1ee7a m\u00ecnh \u0111\u1ec3 \u201ckhuy\u1ebfn ngh\u1ecb \u0111\u1eb7c bi\u1ec7t\u201d baricitinib k\u1ebft h\u1ee3p v\u1edbi steroid \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n COVID-19 n\u1eb7ng ho\u1eb7c nguy k\u1ecbch. <\/span><\/p>\n<p><span>Baricitinib l\u00e0 m\u1ed9t ph\u1ea7n c\u1ee7a nh\u00f3m thu\u1ed1c \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf JAK (<\/span><span>Janus kinase) <\/span><span>. Marconi v\u00e0 c\u00e1c \u0111\u1ed3ng nghi\u1ec7p t\u1ea1i Emory c\u0169ng \u0111\u00e3 nghi\u00ean c\u1ee9u m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf JAK c\u00f3 li\u00ean quan \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 ruxolitinib \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb HIV c\u00f9ng v\u1edbi c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1ng vi r\u00fat. <\/span><\/p>\n<p>Ngu\u1ed3n: Futurity<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Theo m\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi, nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh n\u1eb7ng v\u1edbi COVID-19 c\u1ea7n h\u1ed7 tr\u1ee3 h\u00f4 h\u1ea5p \u0111\u00e3 s\u1ed1ng s\u00f3t v\u1edbi t\u1ef7 l\u1ec7 cao h\u01a1n c\u00f3 \u00fd ngh\u0129a th\u1ed1ng k\u00ea khi \u0111\u01b0\u1ee3c ng\u1eabu nhi\u00ean &hellip; <\/p>\n","protected":false},"author":1,"featured_media":9626,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[82],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v16.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp c\u00f3 th\u1ec3 c\u1ee9u s\u1ed1ng b\u1ec7nh nh\u00e2n COVID c\u1ea7n m\u00e1y th\u1edf - Blog TSK<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cstc.vn\/blogtsk\/thuoc-dieu-tri-viem-khop-co-the-cuu-song-benh-nhan-covid-can-may-tho\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam kh\u1edbp c\u00f3 th\u1ec3 c\u1ee9u s\u1ed1ng b\u1ec7nh nh\u00e2n COVID c\u1ea7n m\u00e1y th\u1edf - Blog TSK\" \/>\n<meta property=\"og:description\" content=\"Theo m\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi, nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh n\u1eb7ng v\u1edbi COVID-19 c\u1ea7n h\u1ed7 tr\u1ee3 h\u00f4 h\u1ea5p \u0111\u00e3 s\u1ed1ng s\u00f3t v\u1edbi t\u1ef7 l\u1ec7 cao h\u01a1n c\u00f3 \u00fd ngh\u0129a th\u1ed1ng k\u00ea khi \u0111\u01b0\u1ee3c ng\u1eabu nhi\u00ean &hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cstc.vn\/blogtsk\/thuoc-dieu-tri-viem-khop-co-the-cuu-song-benh-nhan-covid-can-may-tho\/\" \/>\n<meta property=\"og:site_name\" content=\"Blog TSK\" \/>\n<meta property=\"article:published_time\" content=\"2022-02-18T03:45:49+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/cstc.vn\/blogtsk\/wp-content\/uploads\/2022\/02\/gettyimages-1221058994-2048x2048-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2048\" \/>\n\t<meta property=\"og:image:height\" content=\"1365\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"blogtsk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebSite\",\"@id\":\"https:\/\/cstc.vn\/blogtsk\/#website\",\"url\":\"https:\/\/cstc.vn\/blogtsk\/\",\"name\":\"Blog TSK\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/cstc.vn\/blogtsk\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/cstc.vn\/blogtsk\/thuoc-dieu-tri-viem-khop-co-the-cuu-song-benh-nhan-covid-can-may-tho\/#primaryimage\",\"inLanguage\":\"en-US\",\"url\":\"https:\/\/cstc.vn\/blogtsk\/wp-content\/uploads\/2022\/02\/gettyimages-1221058994-2048x2048-1.jpg\",\"contentUrl\":\"https:\/\/cstc.vn\/blogtsk\/wp-content\/uploads\/2022\/02\/gettyimages-1221058994-2048x2048-1.jpg\",\"width\":2048,\"height\":1365,\"caption\":\"SANTIAGO, CHILE - JUNE 18: Detail as a nurse checks a COVID-19 patient's ventilator on June 18, 2020 in Santiago, Chile. The hospital now has 38 patients with COVID-19 at UCI units. According to official figures, Chile has reported 225,000 positive cases and 3,800 confirmed deaths so far. 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