Nghi\u00ean c\u1ee9u m\u1edbi \u0111\u00e2y cho bi\u1ebft m\u1ed9t lo\u1ea1i vaccine d\u1ea1ng h\u00edt b\u1ea3o v\u1ec7 chu\u1ed9t ch\u1ed1ng l\u1ea1i m\u1ed9t s\u1ed1 ch\u1ee7ng Klebsiella pneumoniae, m\u1ed9t lo\u1ea1i vi khu\u1ea9n c\u00f3 th\u1ec3 g\u00e2y vi\u00eam ph\u1ed5i trong b\u1ec7nh vi\u1ec7n.<\/p>\n
Hi\u1ec7n t\u1ea1i kh\u00f4ng c\u00f3 vaccine \u0111\u01b0\u1ee3c FDA c\u1ea5p ph\u00e9p \u0111\u1ec3 ph\u00f2ng ng\u1eeba ho\u1eb7c \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m tr\u00f9ng, v\u00e0 m\u1ed9t ch\u1ee7ng vi khu\u1ea9n kh\u00e1ng thu\u1ed1c l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y ra \u00edt nh\u1ea5t 7.900 tr\u01b0\u1eddng h\u1ee3p v\u00e0 520 tr\u01b0\u1eddng h\u1ee3p t\u1eed vong m\u1ed7i n\u0103m \u1edf Hoa K\u1ef3. T\u1ed5 ch\u1ee9c Y t\u1ebf Th\u1ebf gi\u1edbi \u0111\u00e3 li\u1ec7t k\u00ea nh\u1eefng ch\u1ee7ng vi khu\u1ea9n kh\u00e1ng kh\u00e1ng sinh n\u00e0y v\u00e0o danh s\u00e1ch \u01b0u ti\u00ean quan tr\u1ecdng c\u1ee7a h\u1ecd \u0111\u1ed1i v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi.<\/p>\n
C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 s\u1eed d\u1ee5ng m\u1ed9t protein m\u00e0ng ngo\u00e0i X t\u1eeb K. pneumoniae v\u00e0 gh\u00e9p n\u1ed1i n\u00f3 v\u1edbi LTA1, m\u1ed9t ch\u1ea5t b\u1ed5 tr\u1ee3 vaccine m\u00e0 h\u1ecd ph\u00e1t tri\u1ec3n t\u1eeb vi khu\u1ea9n E. coli , \u0111\u1ec3 k\u00edch th\u00edch ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch. H\u1ecd \u0111\u00e3 ki\u1ec3m tra t\u00ednh hi\u1ec7u qu\u1ea3 c\u1ee7a vaccine d\u1ea1ng h\u00edt b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng m\u00f4 h\u00ecnh chu\u1ed9t trong \u0111\u00f3 nh\u1eefng con chu\u1ed9t \u0111\u01b0\u1ee3c ti\u00eam vaccine \u0111\u01b0\u1ee3c th\u1eed th\u00e1ch v\u1edbi ba ch\u1ee7ng vi khu\u1ea9n kh\u00e1c nhau \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh ph\u1ea1m vi bao ph\u1ee7 c\u1ee7a vaccine.<\/p>\n
\u201cNguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y ra b\u1ec7nh vi\u00eam ph\u1ed5i tr\u00ean th\u1ebf gi\u1edbi l\u00e0 vi khu\u1ea9n Streptococcus pneumoniae, v\u00e0 kh\u00f4ng c\u00f3 l\u00fd do g\u00ec v\u1ec1 l\u00fd thuy\u1ebft c\u00f4ng ngh\u1ec7 n\u00e0y kh\u00f4ng th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho m\u1ea7m b\u1ec7nh \u0111\u00f3\u201d.<\/p>\n
M\u1ed9t ph\u00e2n t\u00edch mRNA \u0111\u01a1n t\u1ebf b\u00e0o tr\u00ean m\u00f4 h\u00ecnh chu\u1ed9t cho th\u1ea5y r\u1eb1ng c\u00e1c t\u1ebf b\u00e0o T CD4 + \u0111\u01b0\u1ee3c t\u1ea1o ra t\u1eeb vaccine h\u00edt t\u01b0\u01a1ng t\u1ef1 nh\u01b0 c\u00e1c t\u1ebf b\u00e0o \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1edfi vaccine d\u1ef1a tr\u00ean to\u00e0n b\u1ed9 vi khu\u1ea9n b\u1ecb suy y\u1ebfu m\u00e0 nh\u00f3m \u0111\u00e3 s\u1eed d\u1ee5ng trong m\u1ed9t nghi\u00ean c\u1ee9u tr\u01b0\u1edbc \u0111\u00f3.<\/p>\n
Nghi\u00ean c\u1ee9u m\u1edbi tr\u00ean t\u1ea1p ch\u00ed Science Immunology <\/em>c\u0169ng cho th\u1ea5y kh\u1ea3 n\u0103ng b\u1ea3o v\u1ec7 c\u00f3 th\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c \u0111\u1ed9c l\u1eadp v\u1edbi \u0111\u01b0\u1eddng b\u1ec1 m\u1eb7t tr\u00ean vi khu\u1ea9n, v\u00e0 do \u0111\u00f3 c\u00f3 kh\u1ea3 n\u0103ng bao g\u1ed3m nhi\u1ec1u ch\u1ee7ng v\u00e0 lo\u00e0i vi khu\u1ea9n h\u01a1n so v\u1edbi c\u00e1c lo\u1ea1i vaccine vi\u00eam ph\u1ed5i hi\u1ec7n t\u1ea1i.<\/p>\n Trong s\u1ed1 nh\u1eefng ph\u00e1t hi\u1ec7n kh\u00e1c, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 ph\u00e1t hi\u1ec7n ra vaccine d\u1eabn \u0111\u1ebfn hai ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch kh\u00e1c bi\u1ec7t trong ph\u1ed5i bao g\u1ed3m c\u00e1c t\u1ebf b\u00e0o B s\u1ea3n xu\u1ea5t kh\u00e1ng th\u1ec3 c\u0169ng nh\u01b0 m\u1ed9t qu\u1ea7n th\u1ec3 t\u1ebf b\u00e0o T ti\u1ebft ra IL-17, c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 t\u1ebf b\u00e0o Th17.<\/p>\n T\u00e1c gi\u1ea3 t\u01b0\u01a1ng \u1ee9ng Jay Kolls, ch\u1ee7 nhi\u1ec7m khoa n\u1ed9i t\u1ea1i \u0110\u1ea1i h\u1ecdc Tulane, cho bi\u1ebft: \u201cNh\u1eefng t\u1ebf b\u00e0o T n\u00e0y ph\u00e1t t\u00edn hi\u1ec7u c\u01a1 h\u1ecdc \u0111\u1ebfn c\u00e1c t\u1ebf b\u00e0o c\u1ea5u tr\u00fac trong \u0111\u01b0\u1eddng th\u1edf, l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng g\u1ecdi th\u00eam c\u00e1c t\u1ebf b\u00e0o b\u1ea1ch c\u1ea7u \u0111\u1ec3 ch\u1ed1ng l\u1ea1i nhi\u1ec5m tr\u00f9ng.<\/p>\n C\u00f4ng tr\u00ecnh n\u00e0y \u0111\u1eb7t n\u1ec1n t\u1ea3ng cho c\u00e1c lo\u1ea1i vaccine nh\u1eafm v\u00e0o \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p t\u1ea1o ra c\u00e1c t\u1ebf b\u00e0o T b\u1ea3o v\u1ec7 ph\u1ed5i tr\u00ean di\u1ec7n r\u1ed9ng ch\u1ed1ng l\u1ea1i c\u00e1c vi khu\u1ea9n Gram \u00e2m li\u00ean quan, bao g\u1ed3m m\u1ed9t s\u1ed1 lo\u00e0i \u0111a kh\u00e1ng thu\u1ed1c.<\/p>\n Kolls n\u00f3i: \u201cNguy\u00ean nh\u00e2n ch\u00ednh g\u00e2y ra b\u1ec7nh vi\u00eam ph\u1ed5i tr\u00ean th\u1ebf gi\u1edbi l\u00e0 do vi khu\u1ea9n Streptococcus pneumoniae, v\u00e0 kh\u00f4ng c\u00f3 l\u00fd do g\u00ec m\u00e0 c\u00f4ng ngh\u1ec7 n\u00e0y v\u1ec1 m\u1eb7t l\u00fd thuy\u1ebft kh\u00f4ng th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng cho m\u1ea7m b\u1ec7nh \u0111\u00f3\u201d.<\/p>\n \u201cT\u00f4i ngh\u0129 \u0111i\u1ec1u n\u00e0y m\u1edf ra m\u1ed9t n\u1ec1n t\u1ea3ng \u0111\u1ec3 th\u1ef1c s\u1ef1 xem x\u00e9t l\u1ea1i c\u00e1ch ch\u00fang ta s\u1ea3n xu\u1ea5t vaccine ph\u00f2ng b\u1ec7nh nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p. Thay v\u00ec ti\u00eam b\u1eafp, c\u00f3 l\u1ebd ch\u00fang ta n\u00ean ti\u00eam vaccine qua \u0111\u01b0\u1eddng m\u0169i ho\u1eb7c \u0111\u01b0\u1eddng h\u00edt \u0111\u1ec3 \u0111\u01b0a vaccine tr\u1ef1c ti\u1ebfp \u0111\u1ebfn v\u1ecb tr\u00ed nhi\u1ec5m tr\u00f9ng, n\u01a1i c\u1ea7n \u0111\u01b0\u1ee3c b\u1ea3o v\u1ec7 mi\u1ec5n d\u1ecbch nh\u1ea5t\u201d.<\/p>\n Ngu\u1ed3n: Futurity<\/p>\n Ph\u01b0\u01a1ng ph\u00e1p ch\u00ednh l\u00e0 bi\u1ec3u hi\u1ec7n c\u1ee7a tr\u00ed tu\u1ec7. Ai ai c\u0169ng c\u00f3 s\u1eb5n ti\u1ec1m n\u0103ng s\u1eed d\u1ee5ng tr\u00ed tu\u1ec7 c\u1ee7a m\u00ecnh \u0111\u1ec3 v\u1eadn h\u00e0nh c\u00f4ng vi\u1ec7c, cu\u1ed9c s\u1ed1ng. Nh\u1eefng c\u00f4ng c\u1ee5 m\u1ea1nh \u0111\u1ec3 h\u1ed7 tr\u1ee3 ch\u00fang ta \u0111\u01b0a ra c\u00e1c gi\u1ea3i ph\u00e1p t\u1ed1i \u01b0u cho c\u00e1c kh\u00f3 kh\u0103n \u0111\u00e3 \u0111\u01b0\u1ee3c x\u00e2y d\u1ef1ng t\u1eeb r\u1ea5t l\u00e2u b\u1edfi nh\u00e0 khoa h\u1ecdc ng\u01b0\u1eddi Nga. N\u1ebfu b\u1ea1n quan t\u00e2m \u0111\u1ebfn vi\u1ec7c c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng gi\u1ea3i quy\u1ebft v\u1ea5n \u0111\u1ec1 v\u00e0 ra quy\u1ebft \u0111\u1ecbnh m\u1ed9t c\u00e1ch m\u1edbi m\u1ebb, nhanh ch\u00f3ng th\u00ec kh\u00f3a h\u1ecdc PH\u01af\u01a0NG PH\u00c1P LU\u1eacN S\u00c1NG T\u1ea0O v\u00e0 \u0110\u1ed4I M\u1edaI<\/a> t\u1ea1i Trung t\u00e2m S\u00e1ng t\u1ea1o Khoa h\u1ecdc\u2013k\u1ef9 thu\u1eadt (TSK) thu\u1ed9c tr\u01b0\u1eddng Khoa H\u1ecdc T\u1ef1 Nhi\u00ean l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn ph\u00f9 h\u1ee3p. B\u1ea1n c\u00f3 th\u1ec3 \u0111i\u1ec1n th\u00f4ng tin t\u1ea1i \u0111\u00e2y<\/a> ho\u1eb7c li\u00ean h\u1ec7 s\u1ed1 \u0111i\u1ec7n tho\u1ea1i: (028) 38 301 743; 089 668 36 31 \u0111\u1ec3 th\u1ef1c hi\u1ec7n \u0111\u0103ng k\u00fd.<\/p>\n","protected":false},"excerpt":{"rendered":" Nghi\u00ean c\u1ee9u m\u1edbi \u0111\u00e2y cho bi\u1ebft m\u1ed9t lo\u1ea1i vaccine d\u1ea1ng h\u00edt b\u1ea3o v\u1ec7 chu\u1ed9t ch\u1ed1ng l\u1ea1i m\u1ed9t s\u1ed1 ch\u1ee7ng Klebsiella pneumoniae, m\u1ed9t lo\u1ea1i vi khu\u1ea9n c\u00f3 th\u1ec3 g\u00e2y vi\u00eam ph\u1ed5i trong b\u1ec7nh vi\u1ec7n. Hi\u1ec7n t\u1ea1i … <\/p>\n","protected":false},"author":1,"featured_media":9489,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[82],"tags":[],"yoast_head":"\n