C\u00e1c k\u1ef9 s\u01b0 \u0111\u00e3 thi\u1ebft k\u1ebf c\u00e1c protein lai t\u01a1 amyloid v\u00e0 s\u1ea3n xu\u1ea5t ch\u00fang trong vi khu\u1ea9n \u0111\u00e3 \u0111\u01b0\u1ee3c di truy\u1ec1n.<\/p>\n
C\u00e1c s\u1ee3i k\u1ebft qu\u1ea3 m\u1ea1nh h\u01a1n v\u00e0 dai h\u01a1n m\u1ed9t s\u1ed1 lo\u1ea1i t\u01a1 nh\u1ec7n t\u1ef1 nhi\u00ean, \u0111\u01b0\u1ee3c cho l\u00e0 m\u1ed9t trong nh\u1eefng v\u1eadt li\u1ec7u b\u1ec1n v\u00e0 dai nh\u1ea5t tr\u00ean Tr\u00e1i \u0111\u1ea5t<\/p>\n
N\u00f3i m\u1ed9t c\u00e1ch ch\u00ednh x\u00e1c, t\u01a1 nh\u00e2n t\u1ea1o – \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 s\u1ee3i \u201cpolyme amyloid\u201d – kh\u00f4ng ph\u1ea3i do c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u s\u1ea3n xu\u1ea5t v\u1ec1 m\u1eb7t k\u1ef9 thu\u1eadt, m\u00e0 l\u00e0 b\u1edfi vi khu\u1ea9n \u0111\u01b0\u1ee3c bi\u1ebfn \u0111\u1ed5i gen trong ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a Fuzhong Zhang, m\u1ed9t gi\u00e1o s\u01b0 trong khoa n\u0103ng l\u01b0\u1ee3ng, m\u00f4i tr\u01b0\u1eddng v\u00e0 k\u1ef9 thu\u1eadt h\u00f3a h\u1ecdc t\u1ea1i Tr\u01b0\u1eddng K\u1ef9 thu\u1eadt McKelvey thu\u1ed9c \u0110\u1ea1i h\u1ecdc Washington \u1edf St. Louis.<\/p>\n
\u201c\u0110i\u1ec1u n\u00e0y ch\u1ee9ng t\u1ecf r\u1eb1ng ch\u00fang ta c\u00f3 th\u1ec3 thi\u1ebft k\u1ebf sinh h\u1ecdc \u0111\u1ec3 t\u1ea1o ra v\u1eadt li\u1ec7u \u0111\u00e1nh b\u1ea1i v\u1eadt li\u1ec7u t\u1ed1t nh\u1ea5t trong t\u1ef1 nhi\u00ean\u201d.<\/p>\n
Zhang \u0111\u00e3 l\u00e0m vi\u1ec7c v\u1edbi t\u01a1 nh\u1ec7n tr\u01b0\u1edbc \u0111\u00e2y. V\u00e0o n\u0103m 2018, ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a \u00f4ng \u0111\u00e3 thi\u1ebft k\u1ebf vi khu\u1ea9n t\u1ea1o ra t\u01a1 nh\u1ec7n t\u00e1i t\u1ed5 h\u1ee3p v\u1edbi hi\u1ec7u su\u1ea5t ngang b\u1eb1ng v\u1edbi c\u00e1c lo\u1ea1i t\u01a1 t\u1ef1 nhi\u00ean v\u1ec1 t\u1ea5t c\u1ea3 c\u00e1c \u0111\u1eb7c t\u00ednh c\u01a1 h\u1ecdc quan tr\u1ecdng.<\/p>\n
Zhang n\u00f3i: \u201cSau c\u00f4ng tr\u00ecnh tr\u01b0\u1edbc \u0111\u00e2y c\u1ee7a ch\u00fang t\u00f4i, t\u00f4i t\u1ef1 h\u1ecfi li\u1ec7u ch\u00fang t\u00f4i c\u00f3 th\u1ec3 t\u1ea1o ra th\u1ee9 g\u00ec \u0111\u00f3 t\u1ed1t h\u01a1n t\u01a1 nh\u1ec7n b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng n\u1ec1n t\u1ea3ng sinh h\u1ecdc t\u1ed5ng h\u1ee3p c\u1ee7a ch\u00fang t\u00f4i.<\/p>\n
Nh\u00f3m nghi\u00ean c\u1ee9u, bao g\u1ed3m t\u00e1c gi\u1ea3 \u0111\u1ea7u ti\u00ean Jingyao Li, m\u1ed9t nghi\u00ean c\u1ee9u sinh t\u1ea1i ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a Zhang, \u0111\u00e3 s\u1eeda \u0111\u1ed5i tr\u00ecnh t\u1ef1 axit amin c\u1ee7a protein t\u01a1 nh\u1ec7n \u0111\u1ec3 t\u1ea1o ra c\u00e1c \u0111\u1eb7c t\u00ednh m\u1edbi, \u0111\u1ed3ng th\u1eddi gi\u1eef m\u1ed9t s\u1ed1 \u0111\u1eb7c \u0111i\u1ec3m h\u1ea5p d\u1eabn c\u1ee7a t\u01a1 nh\u1ec7n.<\/p>\n
M\u1ed9t v\u1ea5n \u0111\u1ec1 li\u00ean quan \u0111\u1ebfn s\u1ee3i t\u01a1 nh\u1ec7n t\u00e1i t\u1ed5 h\u1ee3p – m\u00e0 kh\u00f4ng c\u00f3 s\u1ef1 thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 t\u1eeb chu\u1ed7i t\u01a1 nh\u1ec7n t\u1ef1 nhi\u00ean – l\u00e0 nhu c\u1ea7u t\u1ea1o ra tinh th\u1ec3 \u03b2-nano, m\u1ed9t th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ee7a t\u01a1 nh\u1ec7n t\u1ef1 nhi\u00ean, g\u00f3p ph\u1ea7n v\u00e0o s\u1ee9c m\u1ea1nh c\u1ee7a n\u00f3.<\/p>\n
Zhang n\u00f3i: \u201cNh\u1ec7n \u0111\u00e3 t\u00ecm ra c\u00e1ch quay s\u1ee3i v\u1edbi m\u1ed9t l\u01b0\u1ee3ng tinh th\u1ec3 nano \u0111\u00e1ng m\u01a1 \u01b0\u1edbc. \u201cNh\u01b0ng khi con ng\u01b0\u1eddi s\u1eed d\u1ee5ng quy tr\u00ecnh k\u00e9o s\u1ee3i nh\u00e2n t\u1ea1o, l\u01b0\u1ee3ng tinh th\u1ec3 nano trong s\u1ee3i t\u01a1 t\u1ed5ng h\u1ee3p th\u01b0\u1eddng th\u1ea5p h\u01a1n so v\u1edbi s\u1ee3i t\u01a1 t\u1ef1 nhi\u00ean c\u1ee7a n\u00f3 “.<\/p>\n
\u0110\u1ec3 gi\u1ea3i quy\u1ebft v\u1ea5n \u0111\u1ec1 n\u00e0y, nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 thi\u1ebft k\u1ebf l\u1ea1i tr\u00ecnh t\u1ef1 t\u01a1 b\u1eb1ng c\u00e1ch \u0111\u01b0a v\u00e0o c\u00e1c tr\u00ecnh t\u1ef1 amyloid c\u00f3 xu h\u01b0\u1edbng h\u00ecnh th\u00e0nh tinh th\u1ec3 \u03b2-nano cao. H\u1ecd \u0111\u00e3 t\u1ea1o ra c\u00e1c protein amyloid cao ph\u00e2n t\u1eed kh\u00e1c nhau b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng ba tr\u00ecnh t\u1ef1 amyloid \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u k\u1ef9 l\u01b0\u1ee1ng l\u00e0m \u0111\u1ea1i di\u1ec7n. C\u00e1c protein thu \u0111\u01b0\u1ee3c c\u00f3 tr\u00ecnh t\u1ef1 axit amin \u00edt l\u1eb7p l\u1ea1i h\u01a1n so v\u1edbi t\u01a1 nh\u1ec7n, do \u0111\u00f3 vi khu\u1ea9n \u0111\u00e3 \u0111\u01b0\u1ee3c bi\u1ebfn \u0111\u1ed5i gen d\u1ec5 d\u00e0ng t\u1ea1o ra ch\u00fang h\u01a1n. Cu\u1ed1i c\u00f9ng, vi khu\u1ea9n \u0111\u00e3 t\u1ea1o ra m\u1ed9t protein amyloid cao ph\u00e2n t\u1eed lai v\u1edbi 128 \u0111\u01a1n v\u1ecb l\u1eb7p l\u1ea1i. S\u1ef1 bi\u1ec3u hi\u1ec7n t\u00e1i t\u1ed5 h\u1ee3p c\u1ee7a protein t\u01a1 nh\u1ec7n v\u1edbi c\u00e1c \u0111\u01a1n v\u1ecb l\u1eb7p l\u1ea1i t\u01b0\u01a1ng t\u1ef1 \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 kh\u00f3.<\/p>\n
Protein c\u00e0ng d\u00e0i, th\u00e0nh c\u00e0ng ch\u1eafc ch\u1ea5t x\u01a1 t\u1ea1o v\u00e0 dai. 128 protein l\u1eb7p l\u1ea1i t\u1ea1o ra s\u1ee3i c\u00f3 \u0111\u1ed9 b\u1ec1n gigapascal (th\u01b0\u1edbc \u0111o l\u1ef1c c\u1ea7n thi\u1ebft \u0111\u1ec3 ph\u00e1 v\u1ee1 s\u1ee3i c\u00f3 \u0111\u01b0\u1eddng k\u00ednh c\u1ed1 \u0111\u1ecbnh), b\u1ec1n h\u01a1n th\u00e9p th\u00f4ng th\u01b0\u1eddng. \u0110\u1ed9 dai c\u1ee7a s\u1ee3i (th\u01b0\u1edbc \u0111o l\u01b0\u1ee3ng n\u0103ng l\u01b0\u1ee3ng c\u1ea7n thi\u1ebft \u0111\u1ec3 l\u00e0m \u0111\u1ee9t s\u1ee3i) cao h\u01a1n Kevlar v\u00e0 t\u1ea5t c\u1ea3 c\u00e1c s\u1ee3i t\u01a1 t\u00e1i t\u1ed5 h\u1ee3p tr\u01b0\u1edbc \u0111\u00e2y. S\u1ee9c m\u1ea1nh v\u00e0 \u0111\u1ed9 d\u1ebbo dai c\u1ee7a n\u00f3 th\u1eadm ch\u00ed c\u00f2n cao h\u01a1n m\u1ed9t s\u1ed1 s\u1ee3i t\u01a1 nh\u1ec7n t\u1ef1 nhi\u00ean \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o.<\/p>\n
C\u1ed9ng t\u00e1c v\u1edbi Young-Shin Jun, gi\u00e1o s\u01b0 khoa n\u0103ng l\u01b0\u1ee3ng, m\u00f4i tr\u01b0\u1eddng, k\u1ef9 thu\u1eadt h\u00f3a h\u1ecdc v\u00e0 nghi\u00ean c\u1ee9u sinh ti\u1ebfn s\u0129 Yaguang Zhu c\u1ee7a c\u00f4, nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 x\u00e1c nh\u1eadn r\u1eb1ng c\u00e1c \u0111\u1eb7c t\u00ednh c\u01a1 h\u1ecdc cao c\u1ee7a s\u1ee3i amyloid cao ph\u00e2n t\u1eed th\u1ef1c s\u1ef1 \u0111\u1ebfn t\u1eeb s\u1ed1 l\u01b0\u1ee3ng tinh th\u1ec3 nano \u03b2 \u0111\u01b0\u1ee3c t\u0103ng c\u01b0\u1eddng.<\/p>\n
Nh\u1eefng protein m\u1edbi n\u00e0y v\u00e0 c\u00e1c s\u1ee3i t\u1ea1o th\u00e0nh kh\u00f4ng ph\u1ea3i l\u00e0 ph\u1ea7n cu\u1ed1i c\u1ee7a c\u00e2u chuy\u1ec7n v\u1ec1 s\u1ee3i t\u1ed5ng h\u1ee3p hi\u1ec7u su\u1ea5t cao trong ph\u00f2ng th\u00ed nghi\u1ec7m Zhang. H\u1ecd ch\u1ec9 m\u1edbi b\u1eaft \u0111\u1ea7u.<\/p>\n
Zhang n\u00f3i: \u201c\u0110i\u1ec1u n\u00e0y ch\u1ee9ng t\u1ecf r\u1eb1ng ch\u00fang ta c\u00f3 th\u1ec3 thi\u1ebft k\u1ebf sinh h\u1ecdc \u0111\u1ec3 t\u1ea1o ra c\u00e1c v\u1eadt li\u1ec7u \u0111\u00e1nh b\u1ea1i v\u1eadt li\u1ec7u t\u1ed1t nh\u1ea5t trong t\u1ef1 nhi\u00ean.<\/p>\n
C\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u n\u00e0y ch\u1ec9 kh\u00e1m ph\u00e1 ba trong s\u1ed1 h\u00e0ng ngh\u00ecn tr\u00ecnh t\u1ef1 amyloid kh\u00e1c nhau c\u00f3 kh\u1ea3 n\u0103ng t\u0103ng c\u01b0\u1eddng c\u00e1c \u0111\u1eb7c t\u00ednh c\u1ee7a t\u01a1 nh\u1ec7n t\u1ef1 nhi\u00ean.<\/p>\n
Li n\u00f3i: \u201cD\u01b0\u1eddng nh\u01b0 c\u00f3 kh\u1ea3 n\u0103ng kh\u00f4ng gi\u1edbi h\u1ea1n trong k\u1ef9 thu\u1eadt v\u1eadt li\u1ec7u hi\u1ec7u su\u1ea5t cao s\u1eed d\u1ee5ng n\u1ec1n t\u1ea3ng c\u1ee7a ch\u00fang t\u00f4i. \u201cC\u00f3 kh\u1ea3 n\u0103ng b\u1ea1n c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng c\u00e1c chu\u1ed7i kh\u00e1c, \u0111\u01b0a ch\u00fang v\u00e0o thi\u1ebft k\u1ebf c\u1ee7a ch\u00fang t\u00f4i v\u00e0 c\u0169ng c\u00f3 \u0111\u01b0\u1ee3c s\u1ee3i quang n\u00e2ng cao hi\u1ec7u su\u1ea5t.\u201d<\/p>\n
Nghi\u00ean c\u1ee9u m\u1edbi xu\u1ea5t hi\u1ec7n tr\u00ean t\u1ea1p ch\u00ed ACS Nano <\/em><\/a>.<\/p>\n B\u1ed9 N\u00f4ng nghi\u1ec7p Hoa K\u1ef3 v\u00e0 V\u0103n ph\u00f2ng Nghi\u00ean c\u1ee9u H\u1ea3i qu\u00e2n \u0111\u00e3 t\u00e0i tr\u1ee3 cho nghi\u00ean c\u1ee9u n\u00e0y.<\/p>\n Ngu\u1ed3n: Futurity<\/p>\n S\u00e1ng t\u1ea1o c\u00f3 ph\u01b0\u01a1ng ph\u00e1p s\u1ebd gi\u00fap ch\u00fang ta v\u01b0\u1ee3t qua c\u00e1c l\u1ed1i m\u00f2n t\u01b0 duy. Li\u1ec7u c\u00f3 n\u01a1i n\u00e0o gi\u1ea3ng d\u1ea1y b\u1ea1n c\u00e1ch s\u00e1ng t\u1ea1o? Kho\u00e1 h\u1ecdc ng\u1eafn h\u1ea1n “PH\u01af\u01a0NG PH\u00c1P LU\u1eacN S\u00c1NG T\u1ea0O v\u00e0 \u0110\u1ed4I M\u1edaI<\/a>” \u0111\u01b0\u1ee3c gi\u1ea3ng d\u1ea1y uy t\u00edn, ch\u1ea5t l\u01b0\u1ee3ng t\u1ea1i Trung t\u00e2m S\u00e1ng t\u1ea1o Khoa h\u1ecdc\u2013k\u1ef9 thu\u1eadt (TSK) thu\u1ed9c tr\u01b0\u1eddng Khoa H\u1ecdc T\u1ef1 Nhi\u00ean s\u1ebd l\u1eddi \u0111\u00e1p h\u1eefu \u00edch cho b\u1ea1n. B\u1ea1n c\u00f3 th\u1ec3 \u0111i\u1ec1n th\u00f4ng tin t\u1ea1i \u0111\u00e2y<\/a> ho\u1eb7c li\u00ean h\u1ec7 s\u1ed1 \u0111i\u1ec7n tho\u1ea1i: (028) 38 301 743; 089 668 36 31 \u0111\u1ec3 th\u1ef1c hi\u1ec7n \u0111\u0103ng k\u00fd.<\/p>\n","protected":false},"excerpt":{"rendered":" C\u00e1c k\u1ef9 s\u01b0 \u0111\u00e3 thi\u1ebft k\u1ebf c\u00e1c protein lai t\u01a1 amyloid v\u00e0 s\u1ea3n xu\u1ea5t ch\u00fang trong vi khu\u1ea9n \u0111\u00e3 \u0111\u01b0\u1ee3c di truy\u1ec1n. C\u00e1c s\u1ee3i k\u1ebft qu\u1ea3 m\u1ea1nh h\u01a1n v\u00e0 dai h\u01a1n m\u1ed9t s\u1ed1 lo\u1ea1i t\u01a1 … <\/p>\n","protected":false},"author":1,"featured_media":9233,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[82],"tags":[],"yoast_head":"\n