{"id":9202,"date":"2021-07-25T17:51:30","date_gmt":"2021-07-25T10:51:30","guid":{"rendered":"http:\/\/trizgyrus.com\/blogtsk\/?p=9202"},"modified":"2021-07-25T17:57:05","modified_gmt":"2021-07-25T10:57:05","slug":"su-tinh-chinh-rna-dan-den-luong-luong-thuc-tu-cay-trong-nhieu-hon-50","status":"publish","type":"post","link":"https:\/\/cstc.vn\/blogtsk\/su-tinh-chinh-rna-dan-den-luong-luong-thuc-tu-cay-trong-nhieu-hon-50\/","title":{"rendered":"S\u1ef1 tinh ch\u1ec9nh RNA d\u1eabn \u0111\u1ebfn l\u01b0\u1ee3ng l\u01b0\u01a1ng th\u1ef1c t\u1eeb c\u00e2y tr\u1ed3ng nhi\u1ec1u h\u01a1n 50%"},"content":{"rendered":"

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u b\u00e1o c\u00e1o r\u1eb1ng thao t\u00e1c v\u1edbi RNA cho ph\u00e9p c\u00e2y tr\u1ed3ng c\u00f3 n\u0103ng su\u1ea5t cao h\u01a1n \u0111\u00e1ng k\u1ec3 v\u00e0 t\u0103ng kh\u1ea3 n\u0103ng ch\u1ecbu h\u1ea1n.<\/p>\n

Trong c\u00e1c th\u1eed nghi\u1ec7m ban \u0111\u1ea7u, vi\u1ec7c b\u1ed5 sung gen m\u00e3 h\u00f3a cho m\u1ed9t lo\u1ea1i protein c\u00f3 t\u00ean l\u00e0 FTO v\u00e0o c\u1ea3 c\u00e2y l\u00faa v\u00e0 c\u00e2y khoai t\u00e2y \u0111\u00e3 l\u00e0m t\u0103ng n\u0103ng su\u1ea5t c\u1ee7a ch\u00fang l\u00ean 50% trong c\u00e1c th\u1eed nghi\u1ec7m th\u1ef1c \u0111\u1ecba.<\/p>\n

C\u00e1c c\u00e2y ph\u00e1t tri\u1ec3n l\u1edbn h\u01a1n \u0111\u00e1ng k\u1ec3, t\u1ea1o ra h\u1ec7 th\u1ed1ng r\u1ec5 d\u00e0i h\u01a1n v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng ch\u1ecbu h\u1ea1n t\u1ed1t h\u01a1n. Ph\u00e2n t\u00edch c\u0169ng cho th\u1ea5y r\u1eb1ng th\u1ef1c v\u1eadt \u0111\u00e3 t\u0103ng t\u1ed1c \u0111\u1ed9 quang h\u1ee3p c\u1ee7a ch\u00fang.<\/p>\n

Chuan He, gi\u00e1o s\u01b0 h\u00f3a h\u1ecdc, h\u00f3a sinh v\u00e0 sinh h\u1ecdc ph\u00e2n t\u1eed t\u1ea1i \u0110\u1ea1i h\u1ecdc Chicago, ng\u01b0\u1eddi d\u1eabn \u0111\u1ea7u nghi\u00ean c\u1ee9u c\u00f9ng v\u1edbi Guifang Jia, gi\u00e1o s\u01b0 t\u1ea1i \u0110\u1ea1i h\u1ecdc B\u1eafc Kinh, cho bi\u1ebft: \u201cS\u1ef1 thay \u0111\u1ed5i th\u1ef1c s\u1ef1 r\u1ea5t \u1ea5n t\u01b0\u1ee3ng. H\u01a1n n\u1eefa, n\u00f3 ho\u1ea1t \u0111\u1ed9ng v\u1edbi h\u1ea7u h\u1ebft m\u1ecdi lo\u1ea1i c\u00e2y m\u00e0 ch\u00fang t\u00f4i \u0111\u00e3 th\u1eed cho \u0111\u1ebfn nay v\u00e0 \u0111\u00f3 l\u00e0 m\u1ed9t s\u1eeda \u0111\u1ed5i r\u1ea5t \u0111\u01a1n gi\u1ea3n \u0111\u1ec3 th\u1ef1c hi\u1ec7n.\u201d<\/p>\n

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u – c\u00f9ng v\u1edbi c\u00e1c chuy\u00ean gia h\u00e0ng \u0111\u1ea7u kh\u00e1c – hy v\u1ecdng v\u1ec1 ti\u1ec1m n\u0103ng c\u1ee7a b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 n\u00e0y, \u0111\u1eb7c bi\u1ec7t l\u00e0 trong b\u1ed1i c\u1ea3nh bi\u1ebfn \u0111\u1ed5i kh\u00ed h\u1eadu v\u00e0 c\u00e1c \u00e1p l\u1ef1c kh\u00e1c \u0111\u1ed1i v\u1edbi h\u1ec7 th\u1ed1ng c\u00e2y tr\u1ed3ng tr\u00ean to\u00e0n th\u1ebf gi\u1edbi.<\/p>\n

\u00d4ng n\u00f3i: \u201c\u0110i\u1ec1u n\u00e0y th\u1ef1c s\u1ef1 cung c\u1ea5p kh\u1ea3 n\u0103ng c\u1ee7a c\u00e1c nh\u00e0 m\u00e1y k\u1ef9 thu\u1eadt \u0111\u1ec3 c\u1ea3i thi\u1ec7n h\u1ec7 sinh th\u00e1i khi t\u00ecnh tr\u1ea1ng \u1ea5m l\u00ean to\u00e0n c\u1ea7u di\u1ec5n ra. Ch\u00fang t\u00f4i d\u1ef1a v\u00e0o th\u1ef1c v\u1eadt cho r\u1ea5t nhi\u1ec1u th\u1ee9 \u2014 m\u1ecdi th\u1ee9 t\u1eeb g\u1ed7, th\u1ef1c ph\u1ea9m v\u00e0 thu\u1ed1c, \u0111\u1ebfn hoa v\u00e0 d\u1ea7u \u2014 v\u00e0 \u0111i\u1ec1u n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng cung c\u1ea5p m\u1ed9t c\u00e1ch \u0111\u1ec3 t\u0103ng ngu\u1ed3n nguy\u00ean li\u1ec7u d\u1ef1 tr\u1eef m\u00e0 ch\u00fang t\u00f4i c\u00f3 th\u1ec3 l\u1ea5y t\u1eeb h\u1ea7u h\u1ebft c\u00e1c lo\u1ea1i th\u1ef1c v\u1eadt\u201d.<\/p>\n

\u201c\u0110\u00e2y l\u00e0 m\u1ed9t c\u00f4ng ngh\u1ec7 r\u1ea5t th\u00fa v\u1ecb v\u00e0 c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3i quy\u1ebft c\u00e1c v\u1ea5n \u0111\u1ec1 \u0111\u00f3i ngh\u00e8o v\u00e0 m\u1ea5t an ninh l\u01b0\u01a1ng th\u1ef1c tr\u00ean quy m\u00f4 to\u00e0n c\u1ea7u \u2014 v\u00e0 c\u0169ng c\u00f3 th\u1ec3 h\u1eefu \u00edch trong vi\u1ec7c \u1ee9ng ph\u00f3 v\u1edbi bi\u1ebfn \u0111\u1ed5i kh\u00ed h\u1eadu,\u201d theo l\u1eddi Michael Kremer, gi\u00e1o s\u01b0 kinh t\u1ebf v\u00e0 Tr\u01b0\u1eddng C\u00f4ng Harris cho bi\u1ebft Ch\u00ednh s\u00e1ch t\u1ea1i \u0110\u1ea1i h\u1ecdc Chicago v\u00e0 ng\u01b0\u1eddi nh\u1eadn gi\u1ea3i Nobel cho c\u00f4ng tr\u00ecnh x\u00f3a \u0111\u00f3i gi\u1ea3m ngh\u00e8o to\u00e0n c\u1ea7u<\/p>\n

T\u0103ng n\u0103ng su\u1ea5t tr\u00ean c\u00e1c c\u00e1nh \u0111\u1ed3ng <\/strong><\/p>\n

Trong nhi\u1ec1u th\u1eadp k\u1ef7, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 l\u00e0m vi\u1ec7c \u0111\u1ec3 th\u00fac \u0111\u1ea9y s\u1ea3n xu\u1ea5t c\u00e2y tr\u1ed3ng trong b\u1ed1i c\u1ea3nh kh\u00ed h\u1eadu ng\u00e0y c\u00e0ng b\u1ea5t \u1ed5n v\u00e0 d\u00e2n s\u1ed1 to\u00e0n c\u1ea7u ng\u00e0y c\u00e0ng t\u0103ng. Nh\u01b0ng c\u00e1c quy tr\u00ecnh nh\u01b0 v\u1eady th\u01b0\u1eddng ph\u1ee9c t\u1ea1p v\u00e0 th\u01b0\u1eddng ch\u1ec9 d\u1eabn \u0111\u1ebfn nh\u1eefng thay \u0111\u1ed5i gia t\u0103ng.<\/p>\n

C\u00e1ch kh\u00e1m ph\u00e1 n\u00e0y ho\u00e0n to\u00e0n kh\u00e1c.<\/p>\n

V\u00e0o n\u0103m 2011, ph\u00f2ng th\u00ed nghi\u1ec7m c\u1ee7a He \u0111\u00e3 m\u1edf ra m\u1ed9t l\u0129nh v\u1ef1c nghi\u00ean c\u1ee9u ho\u00e0n to\u00e0n m\u1edbi b\u1eb1ng c\u00e1ch kh\u00e1m ph\u00e1 ra ch\u00eca kh\u00f3a d\u1eabn \u0111\u1ebfn m\u1ed9t c\u00e1ch kh\u00e1c nhau m\u00e0 gen \u0111\u01b0\u1ee3c bi\u1ec3u hi\u1ec7n \u1edf \u0111\u1ed9ng v\u1eadt c\u00f3 v\u00fa.<\/p>\n

N\u00f3 ch\u1ec9 ra r\u1eb1ng RNA kh\u00f4ng ch\u1ec9 \u0111\u01a1n gi\u1ea3n \u0111\u1ecdc b\u1ea3n thi\u1ebft k\u1ebf DNA v\u00e0 th\u1ef1c hi\u1ec7n n\u00f3 m\u1ed9t c\u00e1ch m\u00f9 qu\u00e1ng; b\u1ea3n th\u00e2n t\u1ebf b\u00e0o c\u0169ng c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh nh\u1eefng ph\u1ea7n n\u00e0o c\u1ee7a b\u1ea3n thi\u1ebft k\u1ebf \u0111\u01b0\u1ee3c th\u1ec3 hi\u1ec7n. N\u00f3 l\u00e0m nh\u01b0 v\u1eady b\u1eb1ng c\u00e1ch \u0111\u1eb7t c\u00e1c d\u1ea5u hi\u1ec7u h\u00f3a h\u1ecdc l\u00ean RNA \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh lo\u1ea1i protein n\u00e0o \u0111\u01b0\u1ee3c t\u1ea1o ra v\u00e0 s\u1ed1 l\u01b0\u1ee3ng.<\/p>\n

\u00d4ng v\u00e0 c\u00e1c \u0111\u1ed3ng nghi\u1ec7p c\u1ee7a m\u00ecnh ngay l\u1eadp t\u1ee9c nh\u1eadn ra r\u1eb1ng \u0111i\u1ec1u n\u00e0y c\u00f3 \u00fd ngh\u0129a l\u1edbn \u0111\u1ed1i v\u1edbi sinh h\u1ecdc. K\u1ec3 t\u1eeb \u0111\u00f3, nh\u00f3m c\u1ee7a \u00f4ng v\u00e0 nh\u1eefng ng\u01b0\u1eddi kh\u00e1c tr\u00ean kh\u1eafp th\u1ebf gi\u1edbi \u0111\u00e3 c\u1ed1 g\u1eafng n\u00e2ng cao hi\u1ec3u bi\u1ebft c\u1ee7a ch\u00fang ta v\u1ec1 qu\u00e1 tr\u00ecnh n\u00e0y v\u00e0 nh\u1eefng g\u00ec n\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn \u0111\u1ed9ng v\u1eadt, th\u1ef1c v\u1eadt v\u00e0 c\u00e1c b\u1ec7nh kh\u00e1c nhau \u1edf ng\u01b0\u1eddi. V\u00ed d\u1ee5, He l\u00e0 \u0111\u1ed3ng s\u00e1ng l\u1eadp c\u1ee7a m\u1ed9t c\u00f4ng ty c\u00f4ng ngh\u1ec7 sinh h\u1ecdc hi\u1ec7n \u0111ang ph\u00e1t tri\u1ec3n c\u00e1c lo\u1ea1i thu\u1ed1c ch\u1ed1ng ung th\u01b0 m\u1edbi d\u1ef1a tr\u00ean vi\u1ec7c nh\u1eafm m\u1ee5c ti\u00eau c\u00e1c protein bi\u1ebfn \u0111\u1ed5i RNA.<\/p>\n

C\u00e2y l\u1edbn h\u01a1n, nhi\u1ec1u c\u00e2y h\u01a1n <\/strong><\/p>\n

\u00d4ng v\u00e0 Guifang Jia, m\u1ed9t c\u1ef1u nghi\u00ean c\u1ee9u sinh sau ti\u1ebfn s\u0129 c\u1ee7a \u0110\u1ea1i h\u1ecdc Chicago v\u00e0 hi\u1ec7n l\u00e0 ph\u00f3 gi\u00e1o s\u01b0 t\u1ea1i \u0110\u1ea1i h\u1ecdc B\u1eafc Kinh, b\u1eaft \u0111\u1ea7u t\u1ef1 h\u1ecfi l\u00e0m th\u1ebf n\u00e0o n\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn sinh h\u1ecdc th\u1ef1c v\u1eadt.<\/p>\n

H\u1ecd t\u1eadp trung v\u00e0o m\u1ed9t lo\u1ea1i protein g\u1ecdi l\u00e0 FTO, lo\u1ea1i protein \u0111\u1ea7u ti\u00ean \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn c\u00f3 t\u00e1c d\u1ee5ng x\u00f3a c\u00e1c d\u1ea5u v\u1ebft h\u00f3a h\u1ecdc tr\u00ean RNA, m\u00e0 Jia t\u00ecm th\u1ea5y khi l\u00e0 m\u1ed9t nh\u00e0 nghi\u00ean c\u1ee9u sau ti\u1ebfn s\u0129 trong nh\u00f3m c\u1ee7a He t\u1ea1i \u0110\u1ea1i h\u1ecdc Chicago.<\/p>\n

C\u00e1c nh\u00e0 khoa h\u1ecdc bi\u1ebft r\u1eb1ng n\u00f3 ho\u1ea1t \u0111\u1ed9ng tr\u00ean RNA \u0111\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a t\u1ebf b\u00e0o \u1edf ng\u01b0\u1eddi v\u00e0 c\u00e1c \u0111\u1ed9ng v\u1eadt kh\u00e1c, v\u00ec v\u1eady h\u1ecd \u0111\u00e3 th\u1eed \u0111\u01b0a gen c\u1ee7a n\u00f3 v\u00e0o c\u00e2y l\u00faa \u2014 v\u00e0 sau \u0111\u00f3 ng\u1ea1c nhi\u00ean quan s\u00e1t khi c\u00e2y l\u1edbn l\u00ean. \u201cT\u00f4i ngh\u0129 ngay l\u00fac \u0111\u00f3 l\u00e0 l\u00fac t\u1ea5t c\u1ea3 ch\u00fang t\u00f4i nh\u1eadn ra r\u1eb1ng ch\u00fang t\u00f4i \u0111ang l\u00e0m m\u1ed9t \u0111i\u1ec1u g\u00ec \u0111\u00f3 \u0111\u1eb7c bi\u1ec7t,\u201d anh \u1ea5y n\u00f3i.<\/p>\n

C\u00e1c c\u00e2y l\u00faa ph\u00e1t tri\u1ec3n g\u1ea5p ba l\u1ea7n c\u00e2y l\u00faa trong \u0111i\u1ec1u ki\u1ec7n ph\u00f2ng th\u00ed nghi\u1ec7m. Khi h\u1ecd tr\u1ed3ng th\u1eed trong c\u00e1c cu\u1ed9c ki\u1ec3m tra th\u1ef1c t\u1ebf tr\u00ean \u0111\u1ed3ng ru\u1ed9ng, c\u00e2y tr\u1ed3ng \u0111\u00e3 t\u0103ng tr\u01b0\u1edfng kh\u1ed1i l\u01b0\u1ee3ng h\u01a1n 50% v\u00e0 n\u0103ng su\u1ea5t l\u00faa cao h\u01a1n 50%. Ch\u00fang m\u1ecdc r\u1ec5 d\u00e0i h\u01a1n, quang h\u1ee3p hi\u1ec7u qu\u1ea3 h\u01a1n v\u00e0 c\u00f3 th\u1ec3 ch\u1ecbu \u0111\u01b0\u1ee3c c\u0103ng th\u1eb3ng do h\u1ea1n h\u00e1n t\u1ed1t h\u01a1n.<\/p>\n

C\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 l\u1eb7p l\u1ea1i c\u00e1c th\u00ed nghi\u1ec7m v\u1edbi c\u00e2y khoai t\u00e2y, ch\u00fang thu\u1ed9c m\u1ed9t h\u1ecd ho\u00e0n to\u00e0n kh\u00e1c. K\u1ebft qu\u1ea3 l\u00e0 nh\u01b0 nhau.<\/p>\n

\u00d4ng n\u00f3i: \u201c\u0110i\u1ec1u \u0111\u00f3 g\u1ee3i \u00fd m\u1ed9t m\u1ee9c \u0111\u1ed9 ph\u1ed5 bi\u1ebfn c\u1ef1c k\u1ef3 th\u00fa v\u1ecb.<\/p>\n

‘C\u00e1ch ti\u1ebfp c\u1eadn ho\u00e0n to\u00e0n m\u1edbi’ cho c\u00e2y tr\u1ed3ng <\/strong><\/p>\n

C\u00e1c nh\u00e0 khoa h\u1ecdc ph\u1ea3i m\u1ea5t nhi\u1ec1u th\u1eddi gian h\u01a1n \u0111\u1ec3 b\u1eaft \u0111\u1ea7u hi\u1ec3u \u0111i\u1ec1u n\u00e0y \u0111ang x\u1ea3y ra nh\u01b0 th\u1ebf n\u00e0o. C\u00e1c th\u00ed nghi\u1ec7m s\u00e2u h\u01a1n cho th\u1ea5y FTO b\u1eaft \u0111\u1ea7u ho\u1ea1t \u0111\u1ed9ng s\u1edbm trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n c\u1ee7a nh\u00e0 m\u00e1y, th\u00fac \u0111\u1ea9y t\u1ed5ng l\u01b0\u1ee3ng sinh kh\u1ed1i m\u00e0 n\u00f3 t\u1ea1o ra.<\/p>\n

C\u00e1c nh\u00e0 khoa h\u1ecdc ngh\u0129 r\u1eb1ng FTO ki\u1ec3m so\u00e1t m\u1ed9t qu\u00e1 tr\u00ecnh \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 m6A, l\u00e0 m\u1ed9t bi\u1ebfn \u0111\u1ed5i quan tr\u1ecdng c\u1ee7a RNA. Trong tr\u01b0\u1eddng h\u1ee3p n\u00e0y, FTO ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch x\u00f3a RNA m6A \u0111\u1ec3 ng\u0103n ch\u1eb7n m\u1ed9t s\u1ed1 t\u00edn hi\u1ec7u b\u00e1o cho c\u00e2y tr\u1ed3ng ch\u1eadm l\u1ea1i v\u00e0 gi\u1ea3m t\u1ed1c \u0111\u1ed9 t\u0103ng tr\u01b0\u1edfng. H\u00e3y t\u01b0\u1edfng t\u01b0\u1ee3ng m\u1ed9t con \u0111\u01b0\u1eddng c\u00f3 r\u1ea5t nhi\u1ec1u \u0111\u00e8n d\u1eebng; N\u1ebfu c\u00e1c nh\u00e0 khoa h\u1ecdc che \u0111\u00e8n \u0111\u1ecf v\u00e0 \u0111\u1ec3 \u0111\u00e8n xanh, ng\u00e0y c\u00e0ng c\u00f3 nhi\u1ec1u xe \u00f4 t\u00f4 di chuy\u1ec3n tr\u00ean \u0111\u01b0\u1eddng.<\/p>\n

Nh\u00ecn chung, c\u00e1c c\u00e2y bi\u1ebfn \u0111\u1ed5i t\u1ea1o ra nhi\u1ec1u RNA h\u01a1n \u0111\u00e1ng k\u1ec3 so v\u1edbi c\u00e1c c\u00e2y \u0111\u1ed1i ch\u1ee9ng.<\/p>\n

Quy tr\u00ecnh \u0111\u01b0\u1ee3c m\u00f4 t\u1ea3 trong b\u00e0i b\u00e1o n\u00e0y li\u00ean quan \u0111\u1ebfn vi\u1ec7c s\u1eed d\u1ee5ng gen FTO \u0111\u1ed9ng v\u1eadt trong th\u1ef1c v\u1eadt. Nh\u01b0ng m\u1ed9t khi c\u00e1c nh\u00e0 khoa h\u1ecdc hi\u1ec3u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 c\u01a1 ch\u1ebf t\u0103ng tr\u01b0\u1edfng n\u00e0y, He cho r\u1eb1ng c\u00f3 th\u1ec3 c\u00f3 nhi\u1ec1u c\u00e1ch kh\u00e1c nhau \u0111\u1ec3 c\u00f3 \u0111\u01b0\u1ee3c hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng t\u1ef1.<\/p>\n

\u201c\u0110\u00e2y l\u00e0 m\u1ed9t ki\u1ec3u ti\u1ebfp c\u1eadn ho\u00e0n to\u00e0n m\u1edbi, c\u00f3 th\u1ec3 kh\u00e1c v\u1edbi vi\u1ec7c ch\u1ec9nh s\u1eeda gen GMO v\u00e0 CRISPR; K\u1ef9 thu\u1eadt n\u00e0y cho ph\u00e9p ch\u00fang t\u00f4i ‘l\u1eadt m\u1ed9t c\u00f4ng t\u1eafc’ trong th\u1ef1c v\u1eadt \u1edf th\u1eddi \u0111i\u1ec3m ban \u0111\u1ea7u trong qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n, \u0111i\u1ec1u n\u00e0y ti\u1ebfp t\u1ee5c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ea3n xu\u1ea5t l\u01b0\u01a1ng th\u1ef1c c\u1ee7a th\u1ef1c v\u1eadt ngay c\u1ea3 sau khi ch\u00fang t\u00f4i lo\u1ea1i b\u1ecf c\u00f4ng t\u1eafc, “\u00f4ng n\u00f3i.<\/p>\n

\u201cC\u00f3 v\u1ebb nh\u01b0 th\u1ef1c v\u1eadt \u0111\u00e3 c\u00f3 l\u1edbp quy \u0111\u1ecbnh n\u00e0y, v\u00e0 t\u1ea5t c\u1ea3 nh\u1eefng g\u00ec ch\u00fang t\u00f4i l\u00e0m l\u00e0 khai th\u00e1c n\u00f3. V\u00ec v\u1eady, b\u01b0\u1edbc ti\u1ebfp theo s\u1ebd l\u00e0 kh\u00e1m ph\u00e1 c\u00e1ch l\u00e0m \u0111i\u1ec1u \u0111\u00f3 b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng di truy\u1ec1n hi\u1ec7n c\u00f3 c\u1ee7a c\u00e2y. ”<\/p>\n

\u00d4ng \u0111ang l\u00e0m vi\u1ec7c v\u1edbi tr\u01b0\u1eddng \u0111\u1ea1i h\u1ecdc v\u00e0 Trung t\u00e2m Kh\u1edfi nghi\u1ec7p v\u00e0 \u0110\u1ed5i m\u1edbi Polsky \u0111\u1ec3 kh\u00e1m ph\u00e1 c\u00e1c kh\u1ea3 n\u0103ng.<\/p>\n

\u201cC\u00e1c nghi\u00ean c\u1ee9u th\u1ef1c \u0111\u1ecba ban \u0111\u1ea7u cho th\u1ea5y n\u00f3 c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c m\u1edf r\u1ed9ng. Ch\u00fang t\u00f4i hy v\u1ecdng s\u1ebd l\u00e0m vi\u1ec7c v\u1edbi c\u00e1c h\u1ecdc vi\u1ec7n v\u00e0 ng\u00e0nh c\u00f4ng nghi\u1ec7p \u0111\u1ec3 hi\u1ec3u s\u00e2u h\u01a1n v\u1ec1 sinh h\u1ecdc n\u00e0y v\u00e0 \u00e1p d\u1ee5ng m\u1ed9t c\u00e1ch an to\u00e0n v\u00e0 r\u1ed9ng r\u00e3i c\u00f4ng ngh\u1ec7 m\u1edbi n\u00e0y, \u201d\u00f4ng n\u00f3i.<\/p>\n

He n\u00f3i: \u201cNgay c\u1ea3 ngo\u00e0i l\u01b0\u01a1ng th\u1ef1c, c\u00f2n c\u00f3 nh\u1eefng h\u1eadu qu\u1ea3 kh\u00e1c c\u1ee7a bi\u1ebfn \u0111\u1ed5i kh\u00ed h\u1eadu. \u201cC\u00f3 l\u1ebd ch\u00fang ta c\u00f3 th\u1ec3 thi\u1ebft k\u1ebf c\u00e1c lo\u1ea1i c\u1ecf \u1edf nh\u1eefng khu v\u1ef1c b\u1ecb \u0111e d\u1ecda c\u00f3 th\u1ec3 ch\u1ecbu \u0111\u01b0\u1ee3c h\u1ea1n h\u00e1n. C\u00f3 l\u1ebd ch\u00fang ta c\u00f3 th\u1ec3 d\u1ea1y m\u1ed9t c\u00e1i c\u00e2y \u1edf Trung T\u00e2y m\u1ecdc r\u1ec5 d\u00e0i h\u01a1n, \u0111\u1ec3 n\u00f3 \u00edt b\u1ecb \u0111\u1ed5 khi c\u00f3 b\u00e3o m\u1ea1nh. C\u00f3 r\u1ea5t nhi\u1ec1u \u1ee9ng d\u1ee5ng ti\u1ec1m n\u0103ng\u201d<\/p>\n

M\u00f4n h\u1ecdc m\u1ea1nh v\u1ec1 kh\u1ea3 n\u0103ng v\u1eadn d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p \u0111\u1ec3 \u1ee9ng ph\u00f3 v\u1edbi c\u00f4ng vi\u1ec7c, cu\u1ed9c s\u1ed1ng ch\u00ednh l\u00e0 PH\u01af\u01a0NG PH\u00c1P LU\u1eacN S\u00c1NG T\u1ea0O v\u00e0 \u0110\u1ed4I M\u1edaI<\/a>. \u0110\u00e2y l\u00e0 ch\u00eca kho\u00e1 \u0111\u1ec3 ti\u1ebfp c\u1eadn v\u1edbi c\u00e1c nguy\u00ean t\u1eafc th\u1ee7 thu\u1eadt gi\u00fap t\u01b0 duy c\u00f3 n\u1ec1n t\u1ea3ng v\u00e0 \u0111\u1ecbnh h\u01b0\u1edbng h\u01a1n. T\u1ea1i Trung t\u00e2m S\u00e1ng t\u1ea1o Khoa h\u1ecdc\u2013k\u1ef9 thu\u1eadt (TSK) thu\u1ed9c tr\u01b0\u1eddng Khoa H\u1ecdc T\u1ef1 Nhi\u00ean l\u00e0 m\u1ed9t n\u01a1i \u0111\u00e1ng tin c\u1eady \u0111\u1ec3 b\u1ea1n theo h\u1ecdc. B\u1ea1n c\u00f3 th\u1ec3 \u0111i\u1ec1n th\u00f4ng tin t\u1ea1i \u0111\u00e2y<\/a> ho\u1eb7c li\u00ean h\u1ec7 s\u1ed1 \u0111i\u1ec7n tho\u1ea1i: (028) 38 301 743; 089 668 36 31 \u0111\u1ec3 th\u1ef1c hi\u1ec7n \u0111\u0103ng k\u00fd.<\/p>\n

Ngu\u1ed3n: Futurity<\/p>\n","protected":false},"excerpt":{"rendered":"

C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u b\u00e1o c\u00e1o r\u1eb1ng thao t\u00e1c v\u1edbi RNA cho ph\u00e9p c\u00e2y tr\u1ed3ng c\u00f3 n\u0103ng su\u1ea5t cao h\u01a1n \u0111\u00e1ng k\u1ec3 v\u00e0 t\u0103ng kh\u1ea3 n\u0103ng ch\u1ecbu h\u1ea1n. Trong c\u00e1c th\u1eed nghi\u1ec7m ban \u0111\u1ea7u, vi\u1ec7c … <\/p>\n","protected":false},"author":1,"featured_media":9203,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[82],"tags":[],"yoast_head":"\nS\u1ef1 tinh ch\u1ec9nh RNA d\u1eabn \u0111\u1ebfn l\u01b0\u1ee3ng l\u01b0\u01a1ng th\u1ef1c t\u1eeb c\u00e2y tr\u1ed3ng nhi\u1ec1u h\u01a1n 50% - Blog TSK<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cstc.vn\/blogtsk\/su-tinh-chinh-rna-dan-den-luong-luong-thuc-tu-cay-trong-nhieu-hon-50\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"S\u1ef1 tinh ch\u1ec9nh RNA d\u1eabn \u0111\u1ebfn l\u01b0\u1ee3ng l\u01b0\u01a1ng th\u1ef1c t\u1eeb c\u00e2y tr\u1ed3ng nhi\u1ec1u h\u01a1n 50% - Blog TSK\" \/>\n<meta property=\"og:description\" content=\"C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u b\u00e1o c\u00e1o r\u1eb1ng thao t\u00e1c v\u1edbi RNA cho ph\u00e9p c\u00e2y tr\u1ed3ng c\u00f3 n\u0103ng su\u1ea5t cao h\u01a1n \u0111\u00e1ng k\u1ec3 v\u00e0 t\u0103ng kh\u1ea3 n\u0103ng ch\u1ecbu h\u1ea1n. 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